MOLECULE

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2

Involved in calcium ion binding The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This phospholipase activity is very sensitive to calcium. May be important for formation and maintenance of the neuronal network in the postnatal brain (By similarity).