Terpene trials of interest

Live now

Recruiting or active

• Behavioral Pharmacology of Orally Administered THC and D-limonene recruiting Phase 1

  Limonene · Subjective Drug Effects, THC, D-limonene · 65 participants · Johns Hopkins University

  The current clinical trial will investigate the effects of orally administered d-limonene (limonene), delta-9-tetrahydrocannabinol (THC) and the combination in healthy adult volunteers.

  NCT06378957 · started 2025-02-14

• CYP2C19 Variants and Limonene Metabolism recruiting Not phased

  Limonene · CYP2C19 Genetic Variants · 20 participants · Stanford University

  The investigators will examine whether a non-invasive screening tool for CYP2C19 genetic variants can be developed by measuring limonene metabolism.

  NCT05078723 · started 2021-10-30

• d-Limonene +Radiation +PlatinumBasedChemo for Xerostomia Prevention in LocallyAdvanced HNSCC recruiting Phase 1

  Limonene · Xerostomia · 40 participants · Stanford University

  This study explores the safety of d-limonene, a commercially-available dietary supplement (food) as a potential therapeutic for the severe dry mouth (xerostomia) experienced by patients with head and neck cancer as a side effect of their anti-cancer treatment.

  NCT04392622 · started 2021-02-15

• Behavioral Pharmacology of THC and Beta-Myrcene not yet recruiting Phase 1

  β-Myrcene Myrcene · Cannabis Use · 32 participants · Johns Hopkins University

  This study will evaluate the pharmacokinetics and pharmacodynamics of vaporized b-myrcene and THC administered via inhalation.

  NCT05432284 · started 2027-07

• Edaravone Dexborneol for Post-Stroke Epilepsy not yet recruiting Phase 3

  Borneol · Post-stroke Epilepsy, Post-stroke Seizure · 160 participants · First Affiliated Hospital of Wenzhou Medical University

  This is a prospective, randomized, double-blind, placebo-controlled, multicenter clinical trial designed to evaluate the efficacy and safety of Edaravone Dexborneol sublingual tablets in preventing late-onset epilepsy in patients with acute ischemic stroke at …

  NCT07604350 · started 2026-06

• Analgesic and Subjective Effects of Terpenes active not recruiting Phase 1

  β-Caryophyllene Myrcene · Pain, Abuse, Drug · 45 participants · University of California, Los Angeles

  The purpose of this research is to assess the analgesic and subjective effects of terpenes administered alone and in combination of THC.

  NCT04451863 · started 2021-12-15

Registered

Completed, withdrawn or unknown status

• Beta Caryophyllene & Apnea Performance completed Not phased

  β-Caryophyllene · EXERCISE PERFORMANCE · 15 participants

  NCT07340996 · 2026-01-15

• The Effectiveness of Lavender Aromatherapy Combined With Slow Breathing Exercises in Improving Occupational Burnout and Sleep Disorders Among Nursing Staff completed Not phased

  Linalool · Sleep Wake Disorders · 70 participants

  NCT06914167 · 2025-04-01

• Pharmacokinetic Study of Terpinolene in Healthy Subjects (PKT Study) completed Not phased

  Terpinolene · Pharmacokinetics of Terpinolene · 11 participants

  NCT06691126 · 2024-11-04

• Development and Evaluation of Computerized Chemosensory Based Orbitofrontal Networks Training for Treatment of Pain completed Phase 1

  β-Caryophyllene · Chronic Pain, Low Back Pain · 86 participants

  NCT06218407 · 2023-04-27

• New Non-invasive Biomarkers of Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) completed Not phased

  Limonene · Healthy, Simple Steatosis (SS), Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) · 172 participants

  NCT06647095 · 2021-09-01

• Phase III Clinical Trial of Y-2 Sublingual Tablets in the Treatment of Acute Ischemic Stroke completed Phase 3

  Borneol · Stroke · 914 participants

  NCT04950920 · 2021-06-28

• Limonene on Regulating Metabolism-related Fatty Liver Disease (MAFLD) and Analysis of TCM Constitution completed EARLY_Phase 1

  Limonene · Fatty Liver · 57 participants

  NCT04853082 · 2021-02-22

• Behavioral Pharmacology of THC and Alpha-pinene completed Phase 1

  α-Pinene · THC, Alpha-pinene · 33 participants

  NCT04130633 · 2020-11-05

• Nasal Irrigation With Chinese Herbal Medicine as an Adjunctive Treatment in Allergic Rhinitis completed Phase 2

  Borneol · Rhinitis, Allergic, Nasal Lavage, Medicine, Chinese Traditional · 38 participants

  NCT05901532 · 2020-11-01

• Alpha-bisabolol for Onychomycosis Treatment completed Phase 1

  α-Bisabolol · Onychomycosis · 60 participants

  NCT04940520 · 2020-06-01

• Alpha-Bisabolol Gel With Antihistamine Action completed Phase 1

  α-Bisabolol · Wounds and Injuries · 20 participants

  NCT05022108 · 2020-04-01

• Lid Wipes Versus Baby Shampoo in Patients With Seborrehic Blepharitis completed Phase 4

  Terpinen-4-ol · Seborrheic Blepharitis · 48 participants

  NCT04441528 · 2018-11-01

• Topical Use of 20% Beta Caryophyllene Alone And In Combination With 0.025% Capsaicin for Pain Caused by Osteoarthritis Of The Knee completed Phase 2

  β-Caryophyllene · Pain · 56 participants

  NCT03152578 · 2017-07-01

• Demodex Blepharitis Treatment Study completed Phase 1

  Terpinen-4-ol · Chronic Blepharitis · 17 participants

  NCT01647217 · 2014-02

• Acupoint Application in Patients With Stable Angina Pectoris (AASAP) completed EARLY_Phase 1

  Borneol · Stable Angina Pectoris · 200 participants

  NCT02029118 · 2012-10

• Limonene Study in Women With Breast Cancer completed Phase 1

  Limonene · Breast Cancer · 59 participants

  NCT01046929 · 2009-08

• Human Breast Tissue Bioavailability of Topically Applied Limonene completed Phase 1

  Limonene · Breast Cancer · 103 participants

  NCT01459172 · 2007-10

• Repeated Open Application Test (ROAT) Study With Hydroperoxides of Linalool unknown Not phased

  Linalool · Allergic Contact Dermatitis · 40 participants

  NCT05858723 · 2023-08

• Limonene for Pulmonary Nodule Chemoprevention unknown Phase 2

  Limonene · Pulmonary Nodules · 160 participants

  NCT05525260 · 2023-02

• Acute Changes In Thermal Pain Response Following Single Oral Dose of Beta-Cary withdrawn Phase 1, Phase 2

  β-Caryophyllene · Beta-Caryophyllene

  NCT04794205 · 2021-09

• Safety, Tolerability and Pharmacokinetics of Y-2(Edaravone And Borneol) Sublingual Tablet unknown Phase 1

  Borneol · Stroke, Acute, Intracranial Hemorrhages · 24 participants

  NCT03495206 · 2018-10-25

Source: ClinicalTrials.gov. A trial is listed when the terpene is named in an intervention or the title. Registration is not a result; follow the NCT id for what each trial reported.