MOLECULE

1-Pyrroline-5-carboxylic acid

1-Pyrroline-5-carboxylic acid, also known as delta(1)-pyrroline-5-carboxylate, belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof. A 1-pyrrolinecarboxylic acid that is 1-pyrroline in which one of the hydrogens at position 5 is replaced by a carboxy group. 1-Pyrroline-5-carboxylic acid is a very strong basic compound (based on its pKa). 1-Pyrroline-5-carboxylic acid exists in all living species, ranging from bacteria to humans. Within humans, 1-pyrroline-5-carboxylic acid participates in a number of enzymatic reactions. In particular, 1-pyrroline-5-carboxylic acid can be converted into L-glutamic acid through the action of the enzyme Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial. In addition, 1-pyrroline-5-carboxylic acid can be converted into L-proline through the action of the enzyme proline dehydrogenase 1, mitochondrial. In humans, 1-pyrroline-5-carboxylic acid is involved in the metabolic disorder called hyperprolinemia type II. 1-Pyrroline-5-carboxylic acid is a potentially toxic compound. 1-Pyrroline-5-carboxylic acid is expected to be in Cannabis as all living plants are known to produce and metabolize it.