MOLECULE

dGDP

dGDP, also known as 2'-deoxy-GDP or 5'-dGDP, belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. dGDP is a moderately basic compound (based on its pKa). dGDP exists in all eukaryotes, ranging from yeast to humans. Within humans, dGDP participates in a number of enzymatic reactions. In particular, dGDP can be converted into dGTP; which is mediated by the enzyme nucleoside diphosphate kinase 6. In addition, dGDP can be biosynthesized from 2'-deoxyguanosine 5'-monophosphate through its interaction with the enzyme guanylate kinase. In humans, dGDP is involved in the metabolic disorder called the gout or kelley-seegmiller syndrome pathway. Outside of the human body, dGDP has been detected, but not quantified in, several different foods, such as chinese bayberries, thistles, french plantains, nopals, and pepper (capsicum). This could make dGDP a potential biomarker for the consumption of these foods. A purine 2'-deoxyribonucleoside 5'-diphosphate having guanine as the nucleobase. dGDP is expected to be in Cannabis as all living plants are known to produce and metabolize it.