MOLECULE

2-oxoglutarate dehydrogenase, mitochondrial

Involved in oxoglutarate dehydrogenase (succinyl-transferring) activity The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).