MOLECULE

3 beta-hydroxysteroid dehydrogenase type 7

Involved in 3-beta-hydroxy-delta5-steroid dehydrogenase activity The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis.