MOLECULE

Beta-cannabispiranol

Cannabispiranol belongs to the class of organic compounds known as indanes. Indanes are compounds containing an indane moiety, which consists of a cyclopentane fused to a benzene ring. Cannapispiranol is also classified as a spiroindane compound. Spiroindane compounds were first isolated and identified as cannabis constituents in 1976. Spiroindane compounds are indane compounds that include two rings which share a single atom (usually a carbon). The simplest example of this type of compound is Spiro[2.2]pentane. Cannapispiranol can also be formally classified as a phenol. There are two known cannabispiranol isomers including Alpha- and Beta-cannabispiranol which differ in the configuration of the hydroxy group on C-4'. The hydroxy group in Beta-cannabispiranol faces "up" and it faces "down" in Alpha-cannabispiranol. Cannabispiranol is an extremely weak basic (essentially neutral) compound (based on its pKa). Cannabispiranol is one of six spirans that have been isolated from Cannabis sativa (DOI: 10.1039/P19820001477). These six spirans have same skeleton of 2 benzene rings and 1 cyclopentane.