MOLECULE

Cannabidivarinic acid

Cannabidivarinic acid or CBDVA, belongs to the class of cannabis compounds known as cannabidiols. It is a non-psychoactive cannabinoid found in cannabis plants. CBDVA is the structural C4 analogue of cannabidiolic acid (CBDA), the natural precursor of cannabidiol (CBD). As such, CBDVA can also be considered a hydroxybenzoic acid derivative. Hydroxybenzoic acid derivatives are compounds containing a hydroxybenzoic acid (or a derivative), which is a benzene ring bearing a carboxyl and, at least, one hydroxyl group. The biosynthesis of CBDVA occurs through the cyclization of the isoprenoid side chain of cannabigerovarinic acid (CBGVA) to yield a cyclohexene moiety, common to all cannabidiol-type cannabinoids (https://doi.org/10.1016/B978-0-12-800756-3.00002-8). Unlike CBDA, research regarding the pharmacological properties of CBDVA is scarce.