MOLECULE

Cannabinodiol

Cannabinodiol (CBND) is a psychoactive cannabinoid (PMID: 30023762). It is present in Cannabis sativa plants at very low concentrations (doi:10.1016/0031-9422(77)80023-X). Cannabinodiol and Cannabinodivarin (CBVD) are the only two known members of the cannabinodiol class of cannabinoids (PMID: 6991645). CBND is the fully aromatized derivative of cannabidiol (CBD). Even though the oxidation of CBD to CBND seems to be a rational mechanism of conversion, it has not been proven experimentally. Oppositely, it has been experimentally demonstrated that CBD occurs through the photochemical reaction of cannabinol (CBN) with UV light, with the opening of the pyrane ring (https://doi.org/10.1039/C39750000797). Cannabinodiol is one of more than 120 cannabinoid compounds that are known to occur in cannabis (PMID: 6991645). Cannabinodiol is also found in cannabis smoke and is volatilized during the combustion of cannabis (https://doi.org/10.1007/978-1-59259-947-9_2).