MOLECULE

Cannabistilbene I

Cannabistilbene I, also known as DMMBD, belongs to the class of organic compounds known as stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. Cannabistilbene I holds two hydroxyl groups (one is methylated) in ring A, both in a meta arrangement in relation to the C2 moiety. Ring B holds one hydroxyl group in para position and is prenylated in the meta position. Cannabistilbene I is a new dihydrostilbene and was obtained as a light oil. Cannabis stilbenoids were first detected and isolated from leaves in 1978, from stem in 1982, and from resin in 1986 (https://doi.org/10.1007/s11101-008-9094-4). Cannabis stilbenoids exhibit antibacterial, anti-inflammatory, antioxidant activities. Cannabistilbene I is one of several non-cannabinoid phenolic compounds that are known to occur in the Cannabis plants (PMID: 28799497).