MOLECULE

Imidazole acetol-phosphate

Imidazole acetol-phosphate belongs to the class of organic compounds known as monoalkyl phosphates. These are organic compounds containing a phosphate group that is linked to exactly one alkyl chain. Imidazole acetol-phosphate is a very strong basic compound (based on its pKa). Imidazole acetol-phosphate exists in all living species, ranging from bacteria to humans. Outside of the human body, Imidazole acetol-phosphate has been detected, but not quantified in, several different foods, such as lima beans, kai-lans, pak choy, globe artichokes, and pomegranates. This could make imidazole acetol-phosphate a potential biomarker for the consumption of these foods. Imidazole acetol-phosphate is created by the breakdown of D-erythro-imidazole-glycerol-phosphate into imidazole acetol-phosphate and H2O. Imidazole acetol-phosphate is involved in the histidine biosynthesis I pathway. Histidinol-phosphate aminotransferase catalyzes this reaction. Imidazole acetol-phosphate reacts with L-glutamate to produce L-histidinol-phosphate and 2-ketoglutarate. Imidazoleglycerol-phosphate dehydratase catalyzes this reaction. Imidazole acetol-phosphate is expected to be in Cannabis as all living plants are known to produce and metabolize it.