MOLECULE
Linalool
Linalool is a monoterpenoid that is octa-1,6-diene substituted by methyl groups at positions 3 and 7 and a hydroxy group at position 3. It has been isolated from plants like Ocimum canum. It has a role as a volatile oil component, an antimicrobial agent, a fragrance and a plant metabolite. It is a monoterpenoid and a tertiary alcohol.
Summary from ChEBI, via PubChem.
Identity
Chemistry
- Formula
- C10H18O
- Molecular weight
- 154.25 g/mol
- IUPAC name
- 3,7-dimethylocta-1,6-dien-3-ol
- InChIKey
- CDOSHBSSFJOMGT-UHFFFAOYSA-N
- SMILES
- CC(=CCCC(C)(C=C)O)C
- PubChem
- CID 6549 ↗
Provenance
Contributing sources
- PubChem
- ChEBI
- LOTUS
Natural occurrence
Found in
- Sweet basil 14
- Hops 7
- L. multiflora 7
- Coriander 6
- African basil 6
- Oregano 6
- Persian zatar 6
- Thyme 6
- Tea 5
- C. deliciosa 5
- Mandarin orange 5
- Torch-ginger 5
- Myrtle 5
- R. officinalis 5
- Sage 5
- Ginger 5
- Shellplant 4
- Lemonscented gum 4
- Lemon grass 4
- Pignut 4
- Spike Lavendar 4
- Water Mint 4
- American basil 4
- Syrian oregano 4
- Greek oregano 4
- Europe sage 4
- T. capitata 4
- Thymus 4
- Chaste-tree 4
- Z. armatum 4
- Shampoo Ginger 4
- Melegueta pepper 3
- Birthwort family 3
- Wormwood 3
- Sweet wormwood 3
- Rape 3
- Camphorwood 3
- Grapefruit 3
- Common turmeric 3
- Zedoary 3
- East Indian lemongrass 3
- Hyssop 3
- M. alternifolia 3
- Korean perilla 3
- French rose 3
- T. spicata 3
- T. longicaulis 3
- Z. bungeanum 3
- Z. multiflora 3
- A. arabica 2
- A. biebersteinii 2
- Blue giant hyssop 2
- A. citriodora 2
- Lemon Verbena 2
- A. triphylla 2
- A. chinensis 2
- A. latilabris 2
- Wild Celery 2
- Mugwort 2
- A. fauriei 2
- A. fauriei var. takaoi 2
- A. megacalyx 2
- B. articulata 2
- B. rufescens 2
- Shrubby Hare's Ear 2
- C. mutabilis 2
- Papaya 2
- Citron 2
- C. unshiu 2
- C. cajucara 2
- C. agathophylla 2
- Curcuma 2
- C. kwangsiensis 2
- C. phaeocaulis 2
- C. wenyujin 2
- Rosha grass 2
- Citronella grass 2
- Cardamom 2
- River redgum 2
- Tumbledown gum 2
- Tasmanian bluegum 2
- Fig 2
- Crane's-bills 2
- H. spicatum 2
- H. dissectum 2
- Heterotropa 2
- Littlebrownjug 2
- Tropical bushmint 2
- Lantana 2
- L. ukambensis 2
- L. trilobum 2
- Lavender 2
- L. puchury-major 2
- L. dulcis 2
- Punktree 2
- Balm 2
- Wild mint 2
- Pennyroyal 2
- Spearmint 2
- Wild bergamot 2
- Sacred lotus 2
- N. falcata 2
- N. viscida 2
- Holy basil 2
- Dittany of Crete 2
- Sweet marjoram 2
- O. minutiflorum 2
- Pot marjoram 2
- Sweet scented geranium 2
- Bayrumtree 2
- Vera cruz pepper 2
- Black pepper 2
- Templetree 2
- Apricot 2
- Damask rose 2
- S. absconditiflora 2
- S. dorisiana 2
- S. dorystaechas 2
- S. hydrangea 2
- Apple-bearing sage 2
- S. syriaca 2
- S. tomentosa 2
- S. cuneifolia 2
- Winter savory 2
- S. amasiaca 2
- S. lyciae 2
- Russian Potato 2
- Hog plum 2
- Yellow woundwort 2
- Feverfew 2
- Mountain germander 2
- T. pseudoscorodonia 2
- T. sandrasicum 2
- Thyme 2
- Cilician thyme 2
- T. fedtschenkoi 2
- T. kotschyanus 2
- T. nummularius 2
- T. revolutus 2
- T. saturejoides 2
- T. sibthorpii 2
- T. zygioides 2
- T. zygis 2
- California laurel 2
- U. tripetala 2
- Baboonwood 2
- Chinese chastetree 2
- Muscadine 2
- Wild Grape 2
- X. sericea 2
- Z. chalybaeum 2
- Z. chalybeum 2
- Z. schinifolium 2
- Corn 2
- Shensi Fir 1
- Sakhalin Fir 1
- A. abrotanoides 1
- A. clavennae 1
- A. cuneatiloba 1
- A. erba-rotta 1
- Yarrow 1
- A. moschata 1
- A. nana 1
- Noble yarrow 1
- A. phrygia 1
- Sneezewort 1
- A. wilhelmsii 1
- A. africanum 1
- Dwarf Sedge 1
- A. simplex 1
- A. cunninghamii 1
- Indian bael 1
- A. rugosa 1
- Cape buchu 1
- Tropical whiteweed 1
- Ground-pine 1
- A. breviligulata 1
- Greater galangal 1
- A. hainanensis 1
- A. katsumadai 1
- Small shell ginger 1
- Amaryllids 1
- A. monospora 1
- A. luma 1
- A. rosaeodora 1
- A. cascarilloides 1
- Soursop 1
- Custard apple 1
- A. laciniatum 1
- Umbellifers 1
- Thale cress 1
- A. asclepiadifolia 1
- A. triangularis 1
- A. afra 1
- A. arborescens 1
- A. capillaris 1
- Tarragon 1
- White wormwood 1
- A. judaica 1
- A. lagocephala 1
- White sagebrush 1
- Davana 1
- A. rubripes 1
- A. rupestris 1
- A. salsoloides 1
- A. thuscula 1
- Canadian wildginger 1
- A. dilatatum 1
- A. lutchuense 1
- A. nipponicum var. nankaiense 1
- A. rigescens 1
- A. trigynum 1
- A. yakusimense 1
- Rooibos 1
- A. scaber 1
- A. buxifolia 1
- A. dulcis 1
- B. dracunculifolia 1
- B. citriodora 1
- Daisy 1
- B. koenigii 1
- Birch 1
- Indian Birch 1
- B. salicifolius 1
- B. tweediei 1
- B. latipinna 1
- B. carteri 1
- Elephant tree 1
- Frankincense 1
- B. echinolabium 1
- B. canariensis 1
- B. mollis 1
- C. incana 1
- Narrow-leaf bottlebrush 1
- C. warszewiczianus 1
- C. odorata 1
- Wild cinnamon 1
- Hemp 1
- C. ipecacuanha 1
- Caraway 1
The 240 best-attested of 695 organisms, ranked by how many independent papers report the compound in each. Occurrence data from LOTUS, across 715 references.
Pharmacology
Protein interactions
-
sentrin-specific protease 8 activity 0 uM
Laboratory measurements of the compound at its own doses. They do not describe any product that contains it.
Reported associations
Disease associations
-
Contact dermatitis, allergic Skin Disease
Associations recorded for the compound itself. A metabolomics association means it was detected or studied in that condition, not that it treats or causes it; an occupational entry describes a hazard of exposure. Neither is a therapeutic claim about any product.
Human evidence in progress
Registered clinical trials
2 registered on ClinicalTrials.gov naming this molecule as an intervention. See all terpene trials.
Evidence
Literature
-
Bioactivity of Linalool Against Culex quinquefasciatus: Repellent and Larvicidal Evaluations
-
Effects of linalool on postoperative peritoneal adhesions in rats
-
Exploration of Chemopreventive Potential of Linalool in Targeting Lung Cancer Biomarkers
-
Linalool acts as a chemical chaperone by inhibiting amyloid-β aggregation
-
Linalool and linalool nerolidol synthases in roses, several genes for little scent
-
Linalool: Therapeutic Indication And Their Multifaceted Biomedical Applications