MOLECULE

Longifolene

Longifolene is a tricyclic sesquiterpene synthesized from isoprene units. The biosynthesis of sesquiterpenes is known to occur mainly through the mevalonic acid pathway (MVA; PMID: 17467679), in the cytosol. Farnesyl diphosphate (FPP) is a key intermediate in the biosynthesis of cyclic sesquiterpenes. FPP undergoes several cyclization reactions to yield a diverse number of cyclic arrangements. Longifolene is a colorless to yellow clear oily liquid found in the high-boiling fraction of certain pine resins. The name is derived from the pine species, Pinus longifolia, from which it was isolated. It has a woody, medicinal, pine, ambergris flavor with a sweet woody rose medicinal fir needle odor ( http://www.thegoodscentscompany.com/data/rw1020031.html#toorgano). It is found in mandarin, artichoke, and star anise fruit and in oils from carrot seeds, hinoki leaf, root and wood and pine needle. Longifolene found in rosemary plants and cannabis plants (PMID: 6991645).