MOLECULE

Pyridoxamine 5'-phosphate

Pyridoxamine 5'-phosphate, also known as pyridoxamine phosphoric acid or pyridoxamine-p, belongs to the class of organic compounds known as pyridoxamine 5'-phosphates. These are heterocyclic aromatic compounds containing a pyridoxamine that carries a phosphate group at the 5'-position. Pyridoxamine 5'-phosphate is a very strong basic compound (based on its pKa). Pyridoxamine 5'-phosphate exists in all living species, ranging from bacteria to humans. Within humans, pyridoxamine 5'-phosphate participates in a number of enzymatic reactions. In particular, pyridoxamine 5'-phosphate can be biosynthesized from pyridoxamine through the action of the enzyme pyridoxal kinase. In addition, pyridoxamine 5'-phosphate can be converted into pyridoxal 5'-phosphate through its interaction with the enzyme pyridoxine-5'-phosphate oxidase. In humans, pyridoxamine 5'-phosphate is involved in vitamin B6 metabolism. Outside of the human body, Pyridoxamine 5'-phosphate is found, on average, in the highest concentration within milk (cow). Pyridoxamine 5'-phosphate has also been detected, but not quantified in, several different foods, such as lovages, small-leaf lindens, cocoa beans, american cranberries, and mango. This could make pyridoxamine 5'-phosphate a potential biomarker for the consumption of these foods. A vitamin B6 phosphate that is the phosphoric ester derivative of pyridoxamine. Pyridoxamine 5'-phosphate is expected to be in Cannabis as all living plants are known to produce and metabolize it.