MOLECULE

Rotundifolone

Rotundifolone belongs to the class of organic compounds known as oxepanes. Oxepanes are compounds containing an oxepane ring, which is a seven-member saturated aliphatic heterocycle with one oxygen and six carbon atoms. Rotundifolone is neutral compound. Rotundifolone has an herbal and minty taste. Rotundifolone is found in highest concentrations in spearmints and cornmints. Rotundifolone has also been detected in herbs and spices. This could make rotundifolone a potential biomarker for the consumption of these foods. Rotundifolone is the major chemical constituent (around 70%) of Mentha crispa essential oil which exibits several biological activities, including antinociceptive, spasmolytic, antimicrobial, larvicidal, trypanocidal, cytotoxic, and antitumoral (PMID: 30057673).