MOLECULE

trans-Sabinene hydrate

Trans-Sabinene hydrate, also known as trans-4-thujanol, belongs to the class of organic compounds known as bicyclic monoterpenoids. These are monoterpenoids containing exactly 2 rings, which are fused to each other. Monoterpenoids are terpenes that contain 10 carbon atoms and are comprised of two isoprene units. The biosynthesis of monoterpenes is known to occur mainly through the methyl-erythritol-phosphate (MEP) pathway in plant cell plastids (PMID: 7640522). Geranyl diphosphate (GPP) is a key intermediate in the biosynthesis of cyclic monoterpenes. GPP undergoes several cyclization reactions to yield a diverse number of cyclic arrangements. Trans-Sabinene hydrate is a neutral, hydrophobic molecule that is practically insoluble in water. It has a woody, balsamic odor. It occurs naturally in a wide number of plants and plant oils including lemon, lime, grapefruit, blood orange, mandarin orange, orange peel, rosemary, nutmeg, pot marjoram, common oregano, and mentha (mint), which makes (+)-trans-sabinene hydrate a potential biomarker for the consumption of these food products. Trans-Sabinene hydrate is one of the terpenoids that has been identified in cannabis plants only in trace amounts (PMID: 6991645). It is one of more than 140 terpenoids found in cannabis and the combination of these terpenoids produces the skunky, fruity odor characteristic of C. savita.